An instrument for
original discovery.

It is already producing results that do not yet exist in the literature.

On long-standing problems in optimization, the system has surpassed the best solutions ever found, compressing more than twenty years of cumulative progress. It has bettered expert teams in cardiac surgery and in vaccine design. It is in operation now.

We have demonstrated its power on a small number of problems. The purpose of this fellowship is to establish how far that power extends — across medicine and clinical science, from cardiology — ischemic disease, heart failure, electrophysiology, structural and congenital disease — to oncology across solid tumors, hematologic malignancies, and treatment-modality optimization; from neurology and critical care to surgery and the perioperative specialties; and across the breadth of clinical practice, from infectious disease and immunology to endocrinology, psychiatry, and beyond.

Not incremental work. Discoveries of the first rank.

As a Fellow, you will pursue the unsolved problems in your field that matter most to you — one, or several — and carry each from formulation to result: defining it, pursuing it on our discovery engine, validating your findings, and publishing them as lead author. Because the instrument compresses the cycle of discovery, some problems will yield in weeks while others hold you for much of the year. The pace, and the portfolio, are yours to set.

You would work under close and sustained mentorship, alongside a cross-disciplinary cohort of comparable ambition. Few are present, in any era, at the founding of a new instrument of discovery. You would belong to the first generation to discover with one.

Where the work reaches in medicine and clinical science.

A sample of the sub-fields in play — far from all of them:

If you hold a hard, unsolved problem in medicine and clinical science — named here or not — it belongs here. This fellowship is defined by the problem, not the list.

The ability to learn, above prior experience with any method.

• A doctorate, or equivalent depth of expertise, in any field — completed, nearing completion, or earned through years of work at the frontier of your domain. Candidates at every career stage are welcome.
• A record of rigorous, original work, and a defining problem you are determined to solve.
• The capacity to learn quickly and to work with an unfamiliar instrument. No background in artificial intelligence or machine learning is required, and full training is provided.
• The ambition to make a discovery that reshapes your field and reaches beyond it.

What the year provides.

• A one-year, full-time, salaried appointment, with compensation commensurate with field and experience.
• Relocation support for international Fellows.
• Lead authorship of the original discoveries you publish.
• Direct and sustained mentorship, and the company of a cohort of equal ambition.
• Access to a discovery instrument available nowhere else.